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Dimenhydrinate
See also Antihistamines
General information
Dimenhydrinate consists of two drugs: diphenhydramine, an ethanolamine, and 8-chlorotheophylline, a xanthine derivative that reduces the sedating properties of diphenhydramine. It is used as an antihistamine.
Organs and systems
Cardiovascular
The typical electrocardiographic changes of Brugada syndrome appeared during infusion of dimenhydrinate in a patient with labyrinthitis; the same changes were later reproduced with intravenous flecainide, confirming the diagnosis of Brugada syndrome [ ].
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