Celiprolol

General information

Celiprolol is a beta ₁ -selective antagonist with partial beta ₂ -agonist activity. In healthy volunteers it caused “particularly unpleasant” subjective adverse reactions, including headache, sleepiness, and feeling cold and generally unwell [ ]. However, it has beneficial effects on lipids, reducing total cholesterol by 6% and low-density lipoproteins by 10% [ ]. Whether this translates into clinical benefit is not known, and celiprolol has no convincing advantages over other beta-blockers [ ].