Lymphoepithelioma-like carcinoma


Definition

  • HPV-related poorly differentiated squamous cell carcinoma morphologically similar to its nasopharyngeal counterpart, characterized by an intense inflammatory response surrounding tumor nests

Clinical features

Epidemiology

  • Rare variant with only a few cases reported

  • Associated with HPV infection; unlike its nasopharyngeal counterpart, it is not associated with Epstein-Barr virus infection.

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