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Chronic nonobstructive pyelonephritis
Definition
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Pathological changes observed in the kidney as the result of vesicoureteral reflux (VUR), intrarenal reflux, and repeated UTIs; also termed reflux nephropathy
Clinical features
Epidemiology
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VUR occurs in approximately 1% of children and is found in 30%–50% of children investigated for UTIs.
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Siblings of children affected with VUR are at higher risk.
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Of the patients receiving dialysis, 11%–20% have a diagnosis of chronic pyelonephritis not otherwise specified.
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