Tubal and Eosinophilic (Oxyphilic) Metaplasia


D efinition Alteration of the epithelial cells consisting of tubular differentiation, including oxyphilic cytoplasm.

Clinical Features

Epidemiology

  • Tubal metaplasia is common, although clonal expansions of tubal metaplasia are less so. Eosinophilic metaplasia is an uncommon entity.

  • Both tubal and eosinophilic metaplasia have been described in conjunction with endometrial intraepithelial neoplasia (EIN) and endometrial adenocarcinoma.

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