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In many hospitals, management of human tissue, specifically tissue allografts, has been centralized. Centralized tissue services coordinate the supply, dispensing, and accounting of products among numerous clinical services and have an infrastructure to efficiently receive, process, store, issue, and manage products.
Tissue suppliers aseptically recover tissue for transplantation from deceased human donors. Suppliers then process and store the recovered tissue. Some of the suppliers use patented processing methods to further refine the tissue through lyophilization and washing/sterilization methods. In compliance with FDA regulations and American Association of Tissue Banks (AATB) Standards, allograft donors should be screened through a review of their medical and social history to identify medical conditions and risk factors associated with infectious diseases, such as Zika virus, that make them ineligible for donation. Allograft donors are thus screened similarly to blood donors. Additionally, microbiological cultures are performed. Currently, disease transmission from transplanted tissue is nearly nonexistent because of advances in donor screening, donor testing, and tissue culture and treatment methods.
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