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Key Concepts Organophosphates cause symptoms by accumulation of acetylcholine. Treat cholinergic symptoms with atropine. Reverse the inhibition of acetylcholinesterase with oximes. Aging, which results in prolonged toxicity, occurs with organophosphate poisoning, but not with carbamates. Chlorinated hydrocarbons can present with…
Key Concepts The opioid toxidrome includes three prominent findings—central nervous system depression, miosis, and, most importantly, respiratory depression—but presentations may be variable. A negative urine screen is often unreliable, and absence of detection should not deter a diagnosis of opioid…