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Botulism and tetanus result from intoxication with the protein neurotoxins elaborated by two related species of Clostridium. The toxins are very similar in structure and function but differ dramatically in their clinical effects because they target different cells in the…
History Tetanus was well known to the ancients; descriptions by Egyptian and Greek physicians survive to the present. They recognized the frequent relationship between injuries and the subsequent development of fatal spasms. Gowers provided the quintessential description of tetanus in…