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Malignant hyperthermia

History Malignant hyperthermia (MH) is a serious and possibly fatal syndrome of skeletal muscle hypermetabolism and calcium dysregulation that occurs when genetically susceptible individuals are exposed to certain anesthetic “triggering” agents, specifically the potent halogenated inhaled volatile anesthetics and the…

Malignant Hyperthermia

Malignant hyperthermia (MH) is a serious and possibly fatal syndrome of skeletal muscle hypermetabolism and calcium dysregulation that occurs when genetically susceptible individuals are exposed to certain anesthetic “triggering” agents- the potent halogenated inhaled volatile anesthetics and the nondepolarizing neuromuscular…