Tag Takayuki Katsuyama

Cytokines in SLE Cytokines produced by the cells of the innate immune system important in SLE pathogenesis include interferon alpha (IFN-α), interleukin (IL)-1, IL-6, tumor necrosis factor (TNF), IL-10, B cell activating factor (BAFF), and a proliferation inducing ligand (APRIL).…

Sex hormones Nine out of ten patients afflicted with SLE are women, indicating that the female gender is an important factor in disease development. A skewed X chromosome-inactivation pattern, sex hormone defects, and reproductive history are factors that contribute to…