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How Should Medications Be Initiated and Titrated to Reduce Acute and Delayed Nausea and Vomiting in the Setting of Chemotherapy?

Introduction and Scope of the Problem Chemotherapy-induced nausea and vomiting (CINV) remains one of the most unpleasant, distressing, and feared symptoms for cancer patients. Without sufficient antiemetic prophylaxis, 30% to more than 90% of patients experience CINV with moderately emetogenic…