Granulocytes are the immune system’s main cellular defense against bacterial and fungal infections. Granulocyte transfusions are used in patients with prolonged neutropenia or functional neutrophil disorders and severe bacterial and fungal infections. Granulocyte transfusion clinical efficacy is not established. However,…
Antibodies to RBC antigens except anti-A and anti-B are called unexpected antibodies. Unexpected RBC antibodies may be alloantibodies reacting against foreign antigens or autoantibodies reacting against self-antigens. Depending on the patient population, 1%–35% of patients have unexpected alloantibodies. Once an…
Pretransfusion testing is performed to select compatible blood components for transfusion, thereby preventing harm to recipient and maximizing posttransfusion survival. AABB Standards require the following: 1. Positive patient identification and their corresponding blood specimen; 2. ABO group and D typing…