Tag STEVEN H. ABMAN

Neonatal and Perinatal Medicine

A physiology-based approach to the respiratory care of children with severe bronchopulmonary dysplasia

Key points Despite advances in perinatal care, including many innovations in cardiorespiratory management of extremely preterm infants, the incidence of bronchopulmonary dysplasia (BPD) and its severity has not decreased over time and remains a major public health problem. Severe BPD…

Neonatology Questions and Controversies: The Newborn Lung
March 22, 2024

Neonatal and Perinatal Medicine

Vascular development and pulmonary hypertension

Key points Lung vascular development occurs as highly choreographed sequence, regulated by hypoxia inducible factors, vascular endothelial growth factor, nitric oxide, and other transcription factors and mediators. In addition to arterial vessels, pulmonary veins are highly reactive vessels that contribute…

Neonatology Questions and Controversies: The Newborn Lung
March 22, 2024

Neonatal and Perinatal Medicine

Persistent Pulmonary Hypertension

Key Points Persistent pulmonary hypertension of the newborn (PPHN) can occur with parenchymal lung disease, with pulmonary hypoplasia, or without associated lung disease ( idiopathic ) and has an incidence of 0.2% in term infants and up to 2% in…

Avery's Diseases of the Newborn
March 22, 2024