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OVERVIEW OF PATHOGENESIS Our understanding of the pathophysiology of the encephalopathy of prematurity continues to evolve significantly. Whereas the focus of this chapter in the prior edition was principally on cerebral white matter injury (WMI), it has become increasingly evident…
White Matter Injury in the Preterm Neonate Preterm birth is a major public health issue affecting an estimated 13 million babies worldwide; one in eight deliveries in the United States are now preterm. Over the past two decades, improved neonatal…
Key Points Intraventricular hemorrhage (IVH) remains a common cause of chronic neurologic morbidity. Despite a gradual decline in the incidence of most grades of IVH, the increased survival of very low birth weight infants has resulted in an increase in…