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Acknowledgments Ruth Grunau’s research is supported by the Canadian Institute of Health Research (CIHR) and a Senior Scientist salary award from the BC Children’s Hospital Research Institute. Simon Beggs’ research is supported by the Medical Research Council (MRC, UK) and…
SUMMARY Neuron–glial interactions are increasingly recognized as being key for physiological and pathological processes in the central nervous system. Microglia in the spinal dorsal horn respond to injury to peripheral nerves by adopting a specific response state characterized by up-regulation…