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Objectives This chapter will: 1. Detail the pathophysiology of ischemia/reperfusion injury and hypothermic protection described in experimental evidence. 2. Discuss the limitations of animal models. 3. Describe three clinical scenarios in which hypothermia is used in clinical settings of ischemia…
Objectives This chapter will: 1. Describe the pathophysiologic mechanisms underlying the development of acute-on-chronic (AoC) kidney dysfunction and its role in the progression toward end-stage kidney disease (ESKD). 2. Identify the most common clinical presentations of critical illness among chronic…