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INTRODUCTION In 1847, only months after the first demonstration of anesthesia, James Simpson, an obstetrician, administered ether to a woman in labor for childbirth. He was quite impressed with the analgesia the new drug induced, as was his patient. Nevertheless,…
Key points ▪ Airway changes throughout pregnancy worsen during labor and delivery as a result of mucosal edema. ▪ Anesthetic agents are not teratogenic; however, inhalation anesthetics and many intravenous agents may trigger developmental apoptosis and other neurologic insults that…