Neurolytic therapy, for the appropriate patient, may result in significant improvement of quality of life and possibly improved function. Few other interventional pain therapies have such extreme risk/benefit profiles requiring targeted patient selection and meticulous procedural technique. Evaluating neurolysis as…
Treatment of chronic pain involves understanding the delicate interplay of nociceptive, neuropathic, and nociplastic mechanisms involved in any given pain syndrome’s pathophysiology. Research into the underlying pathways for chronic pain has provided the mechanistic basis to utilize numerous non-opioid medications…
Introduction Neuropathic pain comprises a wide range of heterogeneous conditions. Various types of neuropathic pain may have distinct pathophysiologic causes and different clinical signs and symptoms. Despite the diversity of conditions classified as “neuropathic pain,” many potentially share common underlying…
Postoperative pain is a complex physiologic reaction to tissue injury. For many patients, the primary concern about surgery is how much pain they will experience after the procedure. Similarly, postoperative pain management is an integral part of anesthesia care. Postoperative…
Key Points ▪ The process of nociception is a dynamic process (i.e., neuroplasticity) with multiple points of modulation. Persistent noxious input may result in relatively rapid neuronal sensitization and possibly persistent pain. ▪ Postoperative pain, especially when poorly controlled, results…