Liver transplantation has made possible the functional cure of several metabolic diseases characterized by inherited genetic defects. In many pediatric transplantation centers, metabolic diseases, most notably α 1 -antitrypsin deficiency, are the second or third most common indication for liver…
Biliary atresia (BA) is the result of an idiopathic, progressive, fibroinflammatory process that affects intra hepatic and extrahepatic bile ducts. It typically presents in the first few weeks of life and without early recognition and surgical treatment progresses rapidly to…
Definition and Historical Perspective Short bowel syndrome (SBS) is defined in children as a critical reduction in the length and absorptive capacity of the gastrointestinal tract, resulting in the inability of the small bowel to adequately absorb nutrients, fluids, and…