Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Graft-versus-host disease (GVHD) is the most significant source of morbidity…
Key Points Classic signs of excess cortisol (Cushing’s) include moon facies, striae, atrophy, and acne. Cortisol deficiency (Addison’s) presents with hyperpigmentation of the skin, nails, and mucous membranes. Excess androgens, as seen in polycystic ovary syndrome and congenital adrenal hyperplasia,…
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory disorder with a complex, multifactorial, and incompletely elucidated pathophysiology. Among relevant host factors are a number of important inflammatory pathways, including increased production of oxygen free radicals, enhanced expression of toll-like receptors…