Endoscopic Biopsy Biopsy Techniques Pinch Biopsy Forceps The most common pinch biopsy forceps used worldwide fits through a 2.8-mm biopsy channel ( Fig. 5.1 ). In general, mucosal samples vary from 4 to 8 mm in size. A smaller-sized forcep that…
Endoscopic Biopsy Biopsy Techniques Pinch Biopsy Forceps The most common pinch biopsy forceps used worldwide fits through a 2.8-mm biopsy channel ( Fig. 5.1 ). In general, mucosal samples vary from 4 to 8 mm in size. A smaller-sized forcep that…
Introduction Normal Histology Microscopically, the pancreas is composed of epithelium (acini, islets, and ducts), connective tissue, and lymphoid tissue. These components may be variably present within any individual pancreatic biopsy, depending on the location and adequacy of the tissue sample.…
Introduction Most benign and malignant neoplasms of the esophagus are epithelial in origin ( Box 24.1 ). Overall, an estimated 17,650 new diagnoses of esophageal carcinoma, and 16,000 deaths, occurred in the United States in 2019. The incidence of esophageal…
Approach To Evaluating Colitis Pathologists are asked to evaluate colorectal biopsy specimens for a variety of reasons, but often only a pattern of injury can be identified, at best. This evaluation is performed with the hope that a specific diagnosis…
Historical Perspective In 1947, at the dawn of gastroscopy, Rudolf Schindler deemed gastritis “one of the most debated diseases of the human body” and predicted that its significance would be discussed “for some time to come.” From the mid-1800s, when…
Introduction Inflammatory disorders of the esophagus are extremely common. Among the most common is gastroesophageal reflux disease (GERD), a chronic condition, affecting as many as 40% of people in the Western world. Because of the ease and frequent use of…
Introduction The conventional approach to teaching about inflammatory disorders of the gastrointestinal (GI) tract is to describe the clinical and histological features of individual disease entities. Unfortunately, rendering a specific diagnosis is not always possible when evaluating mucosal biopsies of…