The clinical practice of transfusion medicine has evolved substantially since the discovery of the ABO system around 1900. Two technological advances set the stage for clinical practice through blood component therapy. First, the introduction of a safe and effective anticoagulant-preservative…
The clinical practice of transfusion medicine has evolved substantially since the discovery of the ABO system around 1900. Two technological advances set the stage for clinical practice through blood component therapy. First, the introduction of a safe and effective anticoagulant-preservative…
Key Points Several regulatory mechanisms have evolved to limit the extent of clot formation after coagulation is triggered. Under normal conditions, these allow hemostasis to be achieved while preventing the growth of a hemostatic plug into an intravascular thrombus. Among…