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Gliomas and glioneuronal tumors constitute the largest and most heterogeneous group of primary central nervous system (CNS) tumors. Normal glia include astrocytes, oligodendrocytes, and ependyma; gliomas are analogously designated as astrocytomas, oligodendrogliomas, and ependymomas to reflect the nonneoplastic cell types…

Gliosis versus glioma Clinical features One of the most challenging differential diagnostic issues in surgical neuropathology is distinguishing between gliosis or reactive astrocytosis and an infiltrating low-grade glioma. Patients with low-grade gliomas may present at any age, although the peak…