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Genetics and Biomarkers in Barrett’s Esophagus and Esophageal Adenocarcinoma
4.1 Introduction Barrett’s esophagus (BE) is the premalignant lesion for esophageal adenocarcinoma (EAC): a malignancy with a very poor prognosis. The progression of BE from benign columnar-lined epithelium (CLE) to adenocarcinoma often occurs through a series of dysplastic stages termed…