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Acknowledgement Substantial material from E. Stephen Buescher’s chapter in Principles and Practice of Pediatric Infectious Diseases , fifth edition, has been used. Phagocytes perform critical roles in human host defense. Polymorphonuclear phagocytes (neutrophils, eosinophils, and basophils) defend against microbial invasion…
Acknowledgment Substantial material from E. Stephen Buescher’s chapter in the previous edition has been used. Although primary immunodeficiency disorders are uncommon, referral for evaluation of these conditions in children with frequent infections is common. Epidemiologic studies show that children aged…