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Abbreviations ALT alanine aminotransferase AST aspartate aminotransferase BMI body mass index CRN Clinical Research Network CT computed tomography ER endoplasmic reticulum GGT γ-glutamyl transferase HCC hepatocellular carcinoma IL-6 interleukin-6 IR insulin resistance KLF6 Krüppel-like factor-6 MRI magnetic resonance imaging NAFL…

Spectrum of fatty liver disease Thomas Addison, known for his description of the eponymous disease, was the first to use the term ‘fatty liver’ in the English medical literature in 1836, most likely referring to alcohol-related liver disease (ALD). Three…