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Acute aortic dissection is an uncommon but life-threatening emergency that requires prompt diagnosis, rapid triage, and immediate treatment. A unified effort across several international centers over the past 20 years has resulted in the establishment of a detailed, prospective registry…

Key points The need for heart valve replacement surgery marks a major milestone in the natural history of valve disease and mandates establishment of a schedule for clinical and echocardiographic surveillance. Surgical repair, especially for primary mitral regurgitation, is preferred…

Additional content is available online at Elsevier eBooks for Practicing Clinicians The past six decades have witnessed extraordinary advancements in patient survival and functional outcomes following heart valve replacement surgery. Continued refinements in prosthetic valve design and performance, surgical and…

Acknowledgments The authors wish to acknowledge the previous contributions of Drs. Eugene Braunwald, Joseph Perloff, Robert O’Rourke, and James A. Shaver, which laid the foundation for this chapter. Additional content is available online at Elsevier eBooks for Practicing Clinicians Evaluation…