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Description of the Pathogen The genus Leishmania comprises vector-borne protozoan parasites that cycle asexually between the digestive tract of the sand fly as a motile flagellated promastigote and, in a wide range of vertebrate hosts (e.g., rodents, canids, hyrax, humans),…
Overview and General Principles Leishmaniasis refers to a diverse spectrum of clinical syndromes caused by infection with protozoan parasites of the genus Leishmania transmitted by the bite of a phlebotomine sand fly. Leishmaniasis can be separated geographically into Old World…