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Introduction Sarcomas of the bone are relatively rare neoplasms with an estimated 2890 new cases in the United States in 2012 [ ]. Because of the rarity of primary bone sarcomas and interpretive uncertainty, management may be delayed from initial…

Over the past several decades, remarkable advances have been seen in the use of imaging for diagnosing, staging, and following up cases of soft tissue neoplasms. In this chapter we discuss the radiologic evaluation of soft tissue tumors, reviewing the…

Etiology Sarcoidosis is a systemic disorder characterized by the accumulation of non-necrotizing granulomas in affected organs, with varying degrees of associated inflammation or fibrosis. Its exact etiology is not known. The pattern of organ involvement and disease progression is variable…

Hyperparathyroidism Etiology A review of more than 20,000 cases of primary hyperparathyroidism found that, in 89% of patients, the cause was a solitary adenoma in the parathyroid gland and that 10% had multiglandular hyperplasia. Parathyroid carcinoma and cysts causing primary…