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D efinition —Infection marked by a shift in the vaginal flora. Caused by a decrease in the normal lactobacilli and an increase in numerous other organisms ( Gardnerella vaginalis , Mobiluncus , Mycoplasma hominis , Prevotella , Porphyromonas , Bacteroides…

D efinition —A fungal infection caused by any member of the Candida species of fungi. Clinical Features Epidemiology Very common, affecting up to 75% of females starting after menarche and increasing in incidence with peaks in the third or fourth…

D efinition —The sensation of pain localized to the vulvar vestibule. Clinical Features Epidemiology Once thought to be a relatively rare condition, it is now known to affect millions of women. You’re Reading a Preview Become a Clinical Tree membership…

D efinition —A granulomatous, inflammatory bowel disease that may spread to involve other sites such as skin and mucosa. Clinical Features Epidemiology Seen in patients with Crohn's disease. Crohn's disease has no gender predilection and usually manifests in the second…

D efinition —A suppurative inflammatory process that can be associated with fistula tract or abscess formation. Clinical Features Epidemiology Most commonly seen in young women. The most common sites of involvement are the axilla and groin. You’re Reading a Preview…

D efinition —Hyperkeratosis marked by discrete, flesh- to white-colored papules to plaques. This entity overlaps with what is called acantholytic dyskeratosis (a term under which other dyskeratoses might fall). In this section we discuss a process that is encountered sporadically.…

D efinition —Autosomal dominant genodermatosis marked by numerous hyperkeratotic papules that usually involve the trunk. Clinical Features Epidemiology Patients present around puberty; however, they can present later in life. Men are more severely affected; however, the incidence is equal in…

D efinition —An autosomal dominant, acantholytic dermatosis with a predilection for moist body creases. Clinical Features Epidemiology It is a rare autosomal dominant disease. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

D efinition —An acquired autoimmune (anti–desmoglein 3 antibodies) blistering disorder that is marked by flaccid bullae and mucosal erosions. Clinical Features Epidemiology Incidence is rare and the disease may affect all age groups. You’re Reading a Preview Become a Clinical…

D efinition —An autoimmune blistering disorder that is the most common cause of subepidermal blisters. Caused by antibodies to a 230 kD plakin (BPAg1) and a 180 kD glycoprotein (BPAg2). Clinical Features Epidemiology Primarily seen in older patients and is commonly associated…