Tag Michelle S. Hirsch MD PhD

Bacterial Vaginosis

D efinition —Infection marked by a shift in the vaginal flora. Caused by a decrease in the normal lactobacilli and an increase in numerous other organisms ( Gardnerella vaginalis , Mobiluncus , Mycoplasma hominis , Prevotella , Porphyromonas , Bacteroides…

Vulvodynia

D efinition —The sensation of pain localized to the vulvar vestibule. Clinical Features Epidemiology Once thought to be a relatively rare condition, it is now known to affect millions of women. You’re Reading a Preview Become a Clinical Tree membership…

Hidradenitis Suppurativa

D efinition —A suppurative inflammatory process that can be associated with fistula tract or abscess formation. Clinical Features Epidemiology Most commonly seen in young women. The most common sites of involvement are the axilla and groin. You’re Reading a Preview…

Epidermolytic Hyperkeratosis

D efinition —Hyperkeratosis marked by discrete, flesh- to white-colored papules to plaques. This entity overlaps with what is called acantholytic dyskeratosis (a term under which other dyskeratoses might fall). In this section we discuss a process that is encountered sporadically.…

Darier’s Disease

D efinition —Autosomal dominant genodermatosis marked by numerous hyperkeratotic papules that usually involve the trunk. Clinical Features Epidemiology Patients present around puberty; however, they can present later in life. Men are more severely affected; however, the incidence is equal in…

Hailey-Hailey Disease

D efinition —An autosomal dominant, acantholytic dermatosis with a predilection for moist body creases. Clinical Features Epidemiology It is a rare autosomal dominant disease. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Pemphigus Vulgaris

D efinition —An acquired autoimmune (anti–desmoglein 3 antibodies) blistering disorder that is marked by flaccid bullae and mucosal erosions. Clinical Features Epidemiology Incidence is rare and the disease may affect all age groups. You’re Reading a Preview Become a Clinical…

Bullous Pemphigoid

D efinition —An autoimmune blistering disorder that is the most common cause of subepidermal blisters. Caused by antibodies to a 230 kD plakin (BPAg1) and a 180 kD glycoprotein (BPAg2). Clinical Features Epidemiology Primarily seen in older patients and is commonly associated…