Introduction Worldwide, cirrhosis leads to more than 1.3 million deaths per year and is the 14th leading cause of death. Cirrhosis results from chronic liver injury and typically takes decades to develop and can be caused by numerous etiologies including…
CHAPTER CONTENTS Iron metabolism and homeostasis 295 Iron absorption and transport 295 Regulation of iron homeostasis 296 Hereditary iron overload 299 Hereditary haemochromatosis 299 Ferroportin disease 306 Hereditary hyperferritinaemia 307 Atransferrinaemia/hypotransferrinaemia 307 Acaeruloplasminaemia 308 Miscellaneous iron overload 308 Neonatal haemochromatosis…
. Developmental and inherited disorders affecting the liver typically present in childhood but may affect individuals of any age. The effect of inherited metabolic disorders on the liver may be considered primary , caused by the accumulation of a metabolite…