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Epidemiology, Risk Factors, Burden and Cost of Acute Rheumatic Fever and Rheumatic Heart Disease
Introduction Acute rheumatic fever (ARF) is an immune-mediated, nonsuppurative consequence of group A β-hemolytic streptococcus (GAS) infection. Although episodes of ARF can result in significant disability, the major impact of ARF at the population level is that it causes long-term,…