The author wishes to acknowledge the contribution of John A. Herring for his work in the previous edition version of this chapter. Osteosarcoma Osteosarcoma (osteogenic sarcoma) is the most common malignant bone tumor in children and adolescents. The most prevalent…
Summary of Key Points Incidence and Epidemiology More than 3000 new cases of bone sarcoma are diagnosed annually in the United States. No specific etiologic agents are identified in the majority of cases. Secondary neoplasms are related to known oncogenic…
Successful treatment of pediatric solid tumors requires collaborative management by the disciplines of surgery, oncology, and radiotherapy. Multimodal therapy achieves the highest rate of cure in many solid tumors and often minimizes long-term morbidity. Smooth collaboration provides optimal care. The…