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Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Plaque psoriasis is a common disorder in which environmental factors…

Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Pseudoxanthoma elasticum (PXE) is a rare, autosomal recessive disorder causing…

Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image The perforating dermatoses are a varied group of conditions characterized…

Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Lichen planus (LP) is a pruritic, papulosquamous disease with characteristic…

Questions Q28.1 What is the rationale strongly supporting the role of interleukin (IL)-17 in the pathogenesis of psoriasis? (Pg. 312) Q28.2 What is the rationale strongly supporting the role of IL-17 in the pathogenesis of psoriatic arthritis? (Pg. 313) Q28.3…

Questions Q27.1 Which IL 12/23 inhibitor is currently approved for the treatment of psoriasis and which biologics are in development? (Pg. 303) Q27.2 What cytokines are inhibited by ustekinumab? (Pg. 303) Q27.3 Which recently discovered immunopathogenic model for psoriasis has…

Key Points Potential risks and benefits associated with phototherapy and drug therapy should be discussed with all patients. Screening examinations should be performed prior to prescribing a therapy with carcinogenic risk. Attention must be paid to treatment interactions that may…