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Definition and historical perspective Erythromelalgia is a rare condition of the extremities characterized by the triad of redness, warmth, and pain. The symptom complex of intermittent acral warmth, pain, and erythema that defines erythromelalgia has been well documented in the…

The neutrophilic dermatoses constitute a heterogeneous but linked spectrum of diseases , with significant overlapping histopathologic findings and similar pathogenic mechanisms and therapeutic approaches. They are often associated with underlying internal diseases, which may have significant morbidity and mortality. Histologically,…

Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Livedoid vasculopathy, or livedoid vasculitis, is a painful ulcerative condition…

Evidence Levels: A Double-blind study B Clinical trial ≥ 20 subjects C Clinical trial < 20 subjects D Series ≥ 5 subjects E Anecdotal case reports Open full size image Antiphospholipid syndrome (APS; Hughes syndrome) is associated with recurrent venous…