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“Losses must be replaced in kind.” Sir Harold Gillies Historical Background Advances in regenerative medicine have opened a new era and enabled reconstruction of devastating soft and bony tissue defects due to trauma, congenital deformities, and neoplastic conditions. Among the…
Introduction More than 89 upper extremities and 30 face transplants have been performed worldwide since 1998, proving that vascularized composite allotransplantation (VCA) is technically feasible and guarantees long-term survival under currently available immunosuppressive regimens. VCA is not a lifesaving procedure,…