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Key Points Uncontrolled hypertension presents a significant health care problem with far-reaching public health and economic consequences. Novel therapies target neurohumoral modulation and mechanical alteration of vascular compliance to treat hypertension. Reduction of the sympathetic nervous output from the renal…

1 What is acute decompensated heart failure? Isn’t it just a worsening of chronic heart failure? Acute decompensated heart failure (ADHF) is a clinical syndrome of worsening signs or symptoms of heart failure (HF) requiring hospitalization or other unscheduled medical…