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Key Points Most fetuses with a prenatal diagnosis of a congenital abnormality can be managed expectantly. For some conditions, in utero referral is mandatory for planned delivery and management after birth. Fetal surgery is only required for conditions that cannot…
Key Points Prenatal ultrasound of the fetal brain in the second and third trimester is described, from basics to advanced neurosonography. Classification of central nervous system anomalies is discussed. The neurodevelopment stage determines some of the pathological conditions; others are…

Introduction Incomplete formation of the fetal diaphragm early in gestation results in a diaphragmatic defect allowing abdominal organs to herniate into the chest. These organs compete for space with the growing lungs, leading to inadequate pulmonary development and to respiratory…

Introduction About 1 in 89 spontaneous conceptions results in the birth of twins. However, with the widespread use of artificial reproductive technologies, the incidence of twinning has increased dramatically worldwide, so that in some countries twins now occur once in…