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Over the past 40 years, there has been a remarkable evolution in our understanding of the pathophysiology, clinical manifestations, and treatment strategies underlying gastroesophageal reflux disease (GERD). Initially synonymous with esophagitis and presence of hiatal hernias, we now understand that…
Introduction Eosinophilic esophagitis (EoE) is a chronic, immune-mediated clinicopathological disease characterized by esophageal symptoms, eosinophilic inflammation localized to the esophagus, and the absence of other causes of eosinophilia. This evolving definition, devised after multiple iterations by a consensus panel, excludes…