Tumors of the digestive tract in children are mostly polypoid. They are also commonly syndromic tumors and tumors with known genetic identification ( Table 372.1 ). They usually manifest as painless rectal bleeding, but when large they can cause obstruction…
Key Points Early onset (<24 hours of age) or new jaundice is never normal and should be investigated. Initial evaluation of a jaundiced infant should always include conjugated and unconjugated bilirubin levels. Infants presenting with jaundice secondary to conjugated hyperbilirubinemia…
43.1 Introduction 43.1.1 Liver Anatomy and Function The cell types within the liver consist of hepatocytes, biliary epithelial cells, sinusoidal-lining cells (Kupffer cells and endothelial cells), stellate cells (formerly known as Ito cells), and cells involved in the immune response.…
Hepatic tumors make up only 1% to 4% of pediatric solid tumors, and most of these are metastatic lesions from an extrahepatic site. The symptoms leading to their diagnosis are usually nonspecific and may be erroneously attributed to an underlying…