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Introduction The number of multiple pregnancies has exponentially increased in the last several decades mainly as a result of women delaying childbearing until they are of advanced maternal age and the expanded use of assisted reproductive techniques. The risk of…

Introduction Chorionic villus sampling (CVS) is a procedure in which small samples of placental tissue are obtained for prenatal diagnosis of aneuploidy or for DNA analysis. CVS is an outpatient procedure usually performed between 10 and 14 weeks' gestation. The…

Introduction Amniocentesis is a procedure in which a transabdominally placed needle is used to withdraw amniotic fluid from the amniotic sac. “Early amniocentesis” (<15 weeks' gestation) should be avoided because of increased complications, including a higher fetal loss rate and…