Synonyms ■ Dermatomyositis ■ Idiopathic inflammatory myopathies ■ Idiopathic inflammatory dermatomyopathies Key features ■ Autoimmune connective tissue disease of uncertain etiology demonstrating a bimodal age distribution with both juvenile and adult forms ■ Clinical and laboratory signs of proximal extensor…
Key Points When evaluating cysts and nodules of the head and neck, consider thyroglossal ductal cysts and thyroid carcinoma metastases. There are many syndromes associated with thyroid cancer with dermatologic manifestations (e.g., Cowden’s disease, multiple mucosal neuroma syndromes, Gardner’s syndrome,…
Key Points Herpes simplex virus infection is a frequent cause of erythema multiforme, while drugs most often cause Stevens–Johnson syndrome and toxic epidermal necrolysis. Erythema multiforme is often self-limited, skin lesions often target-appearing, and mucosal lesions can occur in the…
Key Points Urticaria is characterized by development of wheals and/or angioedema of the skin or mucosa. Individual lesions have a transient nature lasting less than 24 hours. Infection, drugs, chemicals, foods, inhalants, contactants, and physical stimuli are several recognizable triggers…
Key Points Neutrophilic dermatoses encompass a spectrum of diseases marked by cutaneous lesions that on histopathologic examination show intense inflammation composed primarily of mature neutrophils. Behçet’s disease is a neutrophilic dermatosis characterized by an immune-mediated occlusive vasculitis of small, medium,…