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Tuberculosis has caused human disease for more than 4,000 yr and is one of the most important infectious diseases worldwide. Etiology There are 5 closely related mycobacteria in the Mycobacterium tuberculosis complex: M. tuberculosis, M. bovis, M. africanum, M. microti, and…
The genus Mycobacterium consists of a diverse group of acid-fast bacilli (AFB) with a lipid-rich cell wall. The bacilli are aerobic, non–spore-forming, nonmotile, and slightly curved or straight organisms. Mycobacteria take up stain poorly but retain specific dyes despite treatment…