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All skin can react to light because it contains molecules (chromophores) whose chemical structures are capable of absorbing ultraviolet radiation (UVR) or other electromagnetic energy. This absorbed energy is then either re-emitted harmlessly as biologically inactive radiation or diverted to…

Questions Q23.1 What is the pharmacologic importance of food intake and the hepatic ‘first-pass effect’ on methoxsalen bioavailability? (Pg. 264) Q23.2 In which part of the ultraviolet A (UVA) spectrum does methoxsalen have its maximum absorption? (Pg. 264) Q23.3 What…

Key Points Vitamin D is important in bone metabolism. Studies have suggested that vitamin D may lower the risk of developing certain cancers and provide benefit in several diseases, although a causal relationship has yet to be established through clinical…

Key Points Photoprotection includes the complementary strategies of seeking shade when outdoors, using protective clothing, wearing a wide-brimmed hat, application of sunscreen, and wearing sunglasses. Protection from both UVB and UVA is important, and knowledge is also emerging regarding the…