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Biology of Healthy Bone Bone is a dynamic living tissue composed of two major constituents, an organic and a mineral component. The organic components consist of (1) cells, including osteoblast, osteoclast, and osteocytes, and (2) proteins, mainly type 1 collagen…
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Key Points A permanent deformity of the femoral head resulting in premature osteoarthritis is the most important sequela of Legg-Calvé-Perthes disease, also known as Perthes disease. Biologic and mechanical factors contribute to the pathogenesis of the femoral head deformity. The…