Pathophysiology The histologic response to neoadjuvant chemotherapy is one of the most important prognostic factors for patients with bone or soft tissue sarcoma who are scheduled for surgical treatment. Patients whose tumors show little necrosis relative to the fraction of…
Staging encompasses determination of local tumor extent, including skip lesions, and identification or exclusion of distant metastases. Information on local extent and distant spread is a requisite for treatment planning, as discussed in Chapter 98 . Magnetic resonance (MR) is…
Tumors are typically detected on radiographs. A tumor is a space-occupying lesion. It may be neoplastic or non-neoplastic. The non-neoplastic tumor is also referred to as a tumor-like lesion. The group of tumor-like lesions is very heterogeneous and contains normal…
Osteomyelitis is infection of bone or bone marrow. It is usually caused by bacterial infection, less frequently by viruses and fungi and, rarely, parasites. It is subdivided into acute, subacute, and chronic stages, depending on the clinical presentation, which, in…