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Introduction Posttranslational modification of ion channels and related proteins is an important determinant of transcription, splicing, functional expression, localization, and macromolecular assembly. Ion channels and their modifications are important in virtually all physiologic processes and in the heart and vasculature…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Neurologic diseases often affect the heart and vascular system, and in many cases, cardiovascular disease limits life expectancy and reduces quality of life in these patients. As such, cardiologists…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Electrocardiographic Features Atrial fibrillation (AF) is a supraventricular arrhythmia characterized electrocardiographically by low-amplitude baseline oscillations (fibrillatory or f waves from the fibrillating atria) and an irregularly irregular ventricular rhythm.…

Additional content is available online at Elsevier eBooks for Practicing Clinicians Foundations of Cardiac Electrophysiology The Functions of the Cardiac Electrical System While this might come as a surprise to some electrophysiologists, the role of the electrical system of the…

Additional content is available online at Elsevier eBooks for Practicing Clinicians The evaluation of patients with suspected cardiac arrhythmias is highly individualized and must include a comprehensive assessment of the patient. Evaluation of the patient begins with a careful history…