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Summary of Key Points Central nervous system (CNS) anomalies are among the most frequent malformations encountered by antenatal sonography. Ultrasound allows detection of a large proportion of all CNS malformations in early gestation. However, in some cases the findings may…

Introduction Neural tube defects (NTD) are the consequence of a failure in the closure of the neural tube, and differ depending on their localization and extent. The term “neural tube defects” includes defects of the cranial vault, including the spectrum…

Introduction Destructive cerebral lesions are not embryonic malformations, but rather the result of an insult to a normally developed fetal brain. The most common causes are hemorrhage, hypoxia-ischemia, and infections, but the pathophysiology is unclear in many cases. The prognosis…