Tag Francis J. Hornicek

Neurosurgery

Chordomas and Chondrosarcomas of the Axial Skeleton: Emerging Therapies and Future Directions

© 2018 Elsevier Inc. All rights reserved. Please note that the copyright for the original figures submitted by the contributors is owned by Contributors. Introduction: Barriers to Traditional Therapies Chordoma and chondrosarcoma are closely related malignant tumors; in fact, a…

Chordomas and Chondrosarcomas of the Skull Base and Spine
March 6, 2024

Orthopedics

Metastatic Disease Around the Hip

Key Points Metastatic bone disease is a relatively common problem that will become more common as the population ages. Pain and loss of mobility as a result of bone metastasis can severely impair a patient's quality of life. The treatment…

Surgery of the Hip
February 21, 2024

Hematology, Oncology, and Palliative Medicine

Long noncoding RNA and bone sarcoma

Research highlights lncRNAs promote tumorigenesis, chemotherapeutic resistance, and metastasis in bone sarcomas. Notable examples include MALAT1, TUG1, XIST, NEAT1, SNHG12, and UCA1. lncRNAs have emerged as promising diagnostic and prognostic biomarkers, as well as veritable therapeutic targets in bone sarcomas.…

Bone Cancer
December 24, 2023