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Etiology Teratogenic factors due to drugs taken during pregnancy are the best known cause of focal growth disturbances (e.g., thalidomide-associated phocomelia), but sporadic cases of unknown cause are now more frequent. This is due principally to the greater precautions taken…

In this chapter a pragmatic or analytical approach is presented for the detection, staging, grading, and tissue-specific diagnosis of soft tissue tumors (STTs; Fig. 95-1 ). Because of the large number of types of these tumors, classification in a few…

Etiology Marfan syndrome (MFS) is an autosomal dominant disorder. Prevalence and Epidemiology The incidence in the general population is estimated at 1 in 5000 to 10,000. The majority of patients will have familial incidence, although approximately one third of cases…